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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM21A
All Species:
15.45
Human Site:
S504
Identified Species:
42.5
UniProt:
Q641Q2
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q641Q2
NP_001005751.1
1341
147184
S504
A
S
P
E
A
T
V
S
Q
T
D
E
N
K
A
Chimpanzee
Pan troglodytes
XP_001140122
1427
155633
S592
A
L
P
E
A
T
V
S
Q
T
D
E
N
K
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534948
1205
132612
T415
K
E
K
K
E
R
R
T
P
S
D
D
E
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGL7
1334
145292
S498
A
L
P
A
A
S
V
S
Q
T
H
E
S
K
T
Rat
Rattus norvegicus
Q80X08
1328
145131
S496
A
L
P
A
A
S
V
S
Q
T
D
E
N
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234527
1326
146323
T491
P
P
V
A
A
S
T
T
K
E
A
E
S
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001039320
401
44860
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBW7
1469
160880
I599
K
K
S
L
F
D
D
I
E
D
E
D
L
F
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800027
2367
254413
E778
D
P
N
P
S
K
E
E
Q
M
A
R
R
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
N.A.
65.9
N.A.
73.5
72.7
N.A.
N.A.
55.4
N.A.
21.7
N.A.
20.4
N.A.
N.A.
24.1
Protein Similarity:
100
92.6
N.A.
70.6
N.A.
80.5
80
N.A.
N.A.
68.7
N.A.
26.2
N.A.
36.6
N.A.
N.A.
36.2
P-Site Identity:
100
93.3
N.A.
6.6
N.A.
60
80
N.A.
N.A.
13.3
N.A.
0
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
N.A.
40
N.A.
73.3
86.6
N.A.
N.A.
46.6
N.A.
0
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
0
0
34
56
0
0
0
0
0
23
0
0
0
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
12
12
0
0
12
45
23
0
0
12
% D
% Glu:
0
12
0
23
12
0
12
12
12
12
12
56
12
23
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% I
% Lys:
23
12
12
12
0
12
0
0
12
0
0
0
0
45
12
% K
% Leu:
0
34
0
12
0
0
0
0
0
0
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
0
0
0
0
0
0
0
34
0
0
% N
% Pro:
12
23
45
12
0
0
0
0
12
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
56
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
12
12
0
0
0
0
12
12
12
0
% R
% Ser:
0
12
12
0
12
34
0
45
0
12
0
0
23
0
0
% S
% Thr:
0
0
0
0
0
23
12
23
0
45
0
0
0
0
23
% T
% Val:
0
0
12
0
0
0
45
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _